What is Thymosin Alpha-1 and where does it come from?

It's a 28-amino-acid peptide that the thymus gland — the organ that trains your immune cells — makes naturally. Researchers care about it because it appears to help coordinate immune responses rather than acting like a drug that kills cells directly. Its molecular formula is C129H215N33O55 with a molecular weight of 3108.3 g/mol.

What has research shown about Thymosin Alpha-1?

The most cited early work found it slowed the growth of chemically induced mammary tumors in Fisher rats. That points to an indirect, immune-driven effect rather than direct action on the cancer cells. These are preclinical findings and don't predict what happens in humans.

Is Thymosin Alpha-1 FDA approved?

A synthetic version (thymalfasin, brand name Zadaxin) is approved in some countries outside the US for certain conditions, but it is not FDA approved in the United States. The material sold here is not a drug and is supplied for in-vitro and laboratory research use only — not for human or veterinary use.

How does Thymosin Alpha-1 differ from other thymic peptides?

It's one specific, well-defined fragment of the larger thymosin family, isolated because it showed the strongest immune-signaling activity. Unlike broad thymic extracts, it's a single synthetic peptide with a known sequence, which makes it easier to study consistently in the lab.

What is the molecular structure of Thymosin Alpha-1?

It's a linear 28-amino-acid peptide with the formula C129H215N33O55 and a molecular weight of 3108.3 g/mol (CAS 62304-98-7). The key feature is an acetylated N-terminus, which is part of its native structure.

Thymosin Alpha-1

A thymus peptide studied for immune balance

99.74% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$89/ 10mg vial

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99.74% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

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Thymosin Alpha-1 · 10mgLot HPPXJDLive

Purity by HPLC-UV

99.74%

Tested by: Freedom Diagnostics
Tested on: 12 Oct 2026
Net content: 8.37 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

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Live batch data

Freedom Diagnostics

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot HPPXJDVerified

Thymosin Alpha-1 10mg

HPLC purity

99.74%

Pass · Meets spec

Tested

12 Oct 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content8.37 mgPASS

HPLC Chromatogram

Main peak 99.74% · other 0.26%

Alex JohnsonPrincipal Chemist

Authentichain · Verified 1×

Thymosin Alpha-1 10mg — molecular specimen

T-cell activationimmune signaling

Dendritic cellsantigen presentation

Cytokine balanceinflammatory tuning

How Thymosin Alpha-1 works

Researchers study Thymosin Alpha-1 for three main ways it appears to shape the immune response.

T-cell activationimmune signaling

It's studied for helping immature immune cells mature into working T-cells, the fighters that target threats.

Dendritic cellsantigen presentation

Preclinical work suggests it helps antigen-presenting cells flag threats so the rest of the immune system responds.

Cytokine balanceinflammatory tuning

It's investigated for adjusting the signaling molecules that dial immune activity up or down.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of Thymosin Alpha-1 we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

2 batches on record · latest tested 12 Oct 2026

All lab reportsEvery Thymosin Alpha-1 batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Tumor responseClinical

3×

In a randomized trial of 488 people with advanced melanoma, adding thymosin alpha-1 to chemo gave 12 tumor responses, vs 4 in the control group.

12 vs 4 responses

J Clin Oncol 2010 · RCT, n=488

Chemo + interferon4

Chemo + interferon + Tα110

Chemo + Tα112

Tumor responses per treatment group by study end

Vaccine responseClinical

69%

In a placebo-controlled trial of 90 men aged 65 to 99 getting a flu vaccine, 69% given thymosin alpha-1 mounted an antibody response, vs 52% on placebo.

vs 52% on placebo

Placebo52%

Thymosin alpha-169%

Men with a fourfold antibody rise after flu vaccine

J Am Geriatr Soc 1989 · RCT, n=90

Tumor growthPreclinical

−46%

In mouse melanoma models, thymosin alpha-1 slowed tumor growth by 34% to 46% depending on dose, and on its own cut lung metastases by 32%.

vs untreated mice

Lung metastases−32%

Tumor growth−34% to −46%

Reduction vs vehicle in two mouse melanoma models