What exactly is CJC-1295 with DAC and where did it come from?

It's a synthetic analog of growth hormone-releasing hormone (GHRH), the natural brain signal that prompts the pituitary to release growth hormone. It was developed by modifying the first 29 amino acids of GHRH and attaching a drug-affinity complex (DAC) that binds blood albumin. That design was created specifically to solve GHRH's biggest weakness — it normally breaks down within minutes.

What has research actually shown about it?

In early human pharmacology and preclinical studies, single administrations raised growth hormone and IGF-1 levels in a dose-dependent way, with IGF-1 staying elevated for over a week. The standout finding is duration: the DAC modification pushes the half-life to roughly 6–8 days. All of this is research-model data, not evidence of any human-use benefit.

Is CJC-1295 with DAC FDA approved?

No. CJC-1295 with DAC is not approved by the FDA for any use and is not a medicine. The research-grade material sold here is supplied strictly for in-vitro and laboratory research use only — not for human or veterinary use.

How does it differ from CJC-1295 without DAC or from other GH secretagogues?

The key difference is the DAC group. Without DAC, the peptide clears in minutes and acts more like a short-pulse GHRH signal; with DAC it binds albumin and stays active for days, giving sustained signaling. That makes the DAC version a useful tool for studying prolonged GHRH stimulation, whereas the non-DAC form models short bursts.

What is the molecular structure of this peptide?

Its molecular formula is C165H269N47O46 with a molecular weight of 3647.25 g/mol (CAS 446262-90-4). Structurally it's a modified 29-amino-acid GHRH fragment carrying a maleimidopropionic acid drug-affinity complex — the DAC — which is the feature that lets it bind albumin and resist enzymatic breakdown.

CJC-1295 (with DAC)

One weekly amount, days of steady GH pulses

99.33% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$79/ 5mg vial

$39.50 per vial with Buy 1, Get 1 Free

Buy 1, Get 1 Free — add 2 to cart, applied automatically

In stock

99.33% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

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CJC-1295 (with DAC) · 5mgLot CD5-WM2607-001Live

Purity by HPLC-UV

99.33%

Tested by: Accurate Lab Tests
Tested on: 31 Aug 2026
Net content: 8.55 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

Live batch data

Accurate Lab Tests

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot CD5-WM2607-001Verified

CJC-1295 (with DAC) 5mg

HPLC purity

99.33%

Pass · Meets spec

Tested

31 Aug 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content8.55 mgPASS

HPLC Chromatogram

Main peak 99.33% · other 0.67%

Alex JohnsonPrincipal Chemist

Authentichain · Verified 1×

CJC-1295 (with DAC) 5mg — molecular specimen

GHRH receptorpituitary agonist

Albumin bindingDAC complex

IGF-1 axisdownstream output

How CJC-1295 (with DAC) works

CJC-1295 with DAC is studied to work through three linked routes that keep the growth-hormone signal switched on longer.

GHRH receptorpituitary agonist

It binds the GHRH receptor on pituitary cells, the same switch the body's own hormone flips to trigger growth hormone release.

Albumin bindingDAC complex

The DAC group latches onto albumin in the blood, shielding the peptide from breakdown so it circulates for days instead of minutes.

IGF-1 axisdownstream output

Sustained growth hormone release drives the liver to produce IGF-1, the downstream messenger researchers track to gauge activity.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of CJC-1295 (with DAC) we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

3 batches on record · latest tested 31 Aug 2026

All lab reportsEvery CJC-1295 (with DAC) batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Growth hormoneClinical

10×

In placebo-controlled trials in healthy adults, one injection of CJC-1295 raised growth hormone 2- to 10-fold, depending on dose, for 6 days or more.

vs levels before injection

JCEM 2006 · 2 placebo-controlled RCTs

Before injection1×

Lowest dose2×

Highest dose10×

Rise in mean blood GH after one injection

Lasting effectClinical

28 days

In the same trials, IGF-1 rose 1.5- to 3-fold for 9 to 11 days after one CJC-1295 injection, and repeat doses kept it above baseline for up to 28 days.

half-life of 5.8 to 8.1 days

Day 6+

GH still 2–10× higher

Day 9–11

IGF-1 still 1.5–3× higher

Day 28

IGF-1 above baseline, repeat doses

How long the effect lasted in healthy adults

JCEM 2006 · 2 placebo-controlled RCTs

Baseline GHClinical

7.5×

In healthy young men, one injection of CJC-1295 raised baseline growth hormone 7.5-fold a week later and IGF-1 by 45%, with natural GH pulses unchanged.

vs the same men before

Trough GH7.5×

Mean GH+46%

IGF-1+45%

Change one week after a single injection

JCEM 2006 · overnight sampling study