What is 5-Amino-1MQ and why does it matter?

5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme that's especially active in fat and liver tissue and helps regulate how cells handle energy. Researchers got interested because blocking this enzyme in preclinical models appears to shift fat cells toward burning energy rather than storing it. It's studied as a metabolic research target, not a finished therapeutic.

What has research suggested about how it works?

In preclinical work, inhibiting NNMT is associated with reduced fat storage and increased cellular energy use — and notably without the animals eating less. That points to changed metabolism inside the cell rather than appetite suppression. These are early-stage, model-based observations and shouldn't be read as human outcomes.

Is 5-Amino-1MQ FDA approved?

No. 5-Amino-1MQ is not approved by the FDA for any use and is not a drug, food or medical device. There is no approved product built on it. The material sold here is supplied strictly for in-vitro and laboratory research use only — not for human or veterinary use.

How is 5-Amino-1MQ used in research settings?

It's used as a chemical tool to probe the NNMT pathway in cell and animal models of metabolism and obesity. Because it selectively targets one enzyme, researchers use it to test what happens to fat-cell energy handling when that enzyme is switched off. All such work is in-vitro or preclinical.

What is the molecular structure of 5-Amino-1MQ?

Its molecular formula is C10H11N2+ with a molecular weight of about 159.21 g/mol, and its CAS number is 685079-15-6. Structurally it's a methylquinolinium-based small molecule carrying an amino group, which is the feature tied to its NNMT-blocking activity. Purity of this lot is ≥99% by HPLC-UV with identity confirmed by LC-MS.

5-Amino-1MQ

The fat-cell enzyme blocker turning heads in metabolic research

99.91% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$89/ 50mg vial

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99.91% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

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5-Amino-1MQ · 50mgLot 2CTMHELive

Purity by HPLC-UV

99.91%

Tested by: Freedom Diagnostics
Tested on: 17 Sept 2026
Net content: 55.17

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

Live batch data

Freedom Diagnostics

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot 2CTMHEVerified

5-Amino-1MQ 50mg

HPLC purity

99.91%

Pass · Meets spec

Tested

17 Sept 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content55.17PASS

HPLC Chromatogram

Main peak 99.91% · other 0.09%

Alex JohnsonPrincipal Chemist

Authentichain

NNMT blockenzyme inhibitor

NAD+ salvagecofactor recycling

Energy expenditureadipose metabolism

How 5-Amino-1MQ works

Researchers study 5-Amino-1MQ as working through three connected metabolic routes inside the cell.

NNMT blockenzyme inhibitor

It's studied for inhibiting nicotinamide N-methyltransferase, the enzyme that helps fat cells stash energy rather than burn it.

NAD+ salvagecofactor recycling

By freeing up nicotinamide, it may push more NAD+ recycling, a cofactor tied to how cells generate and spend energy.

Energy expenditureadipose metabolism

In preclinical models it's linked to fat cells raising their energy use, a route being explored independent of appetite.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of 5-Amino-1MQ we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

6 batches on record · latest tested 17 Sept 2026

All lab reportsEvery 5-Amino-1MQ batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Grip strengthPreclinical

+40%

In aged mice, 5-amino-1MQ raised grip strength by about 40%, vs 20% from intense exercise alone, and by 60% when the two were combined.

vs untreated, inactive aged mice

Sci Rep 2024 · mouse study

UntreatedBaseline

Exercise+20%

5-amino-1MQ+40%

Both+60%

Grip strength vs untreated aged mice, week 6

Fat tissuePreclinical

−35%

In obese mice on a high-fat diet, 11 days of 5-amino-1MQ shrank white fat mass by about 35%, while food intake stayed the same.

vs untreated obese mice

UntreatedBaseline

5-amino-1MQ−35%

White fat pad mass after 11 days

Biochem Pharmacol 2018 · mouse study

Muscle repairPreclinical

+70%

In 24-month-old mice recovering from a muscle injury, 5-amino-1MQ led to nearly 2-fold larger muscle fibers and about 70% more muscle force than untreated mice.

vs untreated aged mice

UntreatedBaseline

5-amino-1MQ+70%

Peak force of the injured leg muscle

Biochem Pharmacol 2019 · mouse study