The first 29 amino acids of growth hormone-releasing hormone — the shortest fragment that retains the full activity of the parent hypothalamic peptide.

How does it differ from ghrelin-receptor compounds?

It acts at the GHRH receptor on pituitary somatotrophs, whereas compounds such as ipamorelin act at the ghrelin receptor. They enter the same axis at different points, which is why both appear in the literature.

Why only 29 amino acids?

Structure-activity work established that the first 29 residues carry the full activity of the parent hormone, so the shorter fragment is a simpler and more stable research tool.

10 mg of lyophilised powder in a sealed crimp-top vial, assayed at ≥99% purity by HPLC-UV with identity confirmed by LC-MS.

Is a certificate of analysis available?

Yes. A batch-level certificate is issued against the lot number and covers the material you receive.

Sermorelin

GHRH(1-29) — the shortest fully active fragment

99.84% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$89/ 10mg vial

$44.50 per vial with Buy 1, Get 1 Free

Buy 1, Get 1 Free — add 2 to cart, applied automatically

In stock

99.84% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

or browse the lot archive

Sermorelin · 10mgLot MJ12D5Live

Purity by HPLC-UV

99.84%

Tested by: Freedom Diagnostics
Tested on: 17 Aug 2026
Net content: 11.55 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

Live batch data

Freedom Diagnostics

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot MJ12D5Verified

Sermorelin 10mg

HPLC purity

99.84%

Pass · Meets spec

Tested

17 Aug 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content11.55 mgPASS

HPLC Chromatogram

Main peak 99.84% · other 0.16%

Alex JohnsonPrincipal Chemist

Authentichain

GHRH receptorpituitary

Somatotroph signallingcAMP

Pulsatile releaseendocrine models

How Sermorelin works

Researchers study Sermorelin as acting through three broad routes.

GHRH receptorpituitary

It is studied as an agonist at the GHRH receptor expressed on somatotroph cells of the anterior pituitary.

Somatotroph signallingcAMP

Cell work examines the cAMP cascade downstream of receptor engagement.

Pulsatile releaseendocrine models

Preclinical studies investigate the pulsatile pattern of release rather than a sustained signal.

For research use only. Mechanisms described reflect published preclinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of Sermorelin we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

4 batches on record · latest tested 17 Aug 2026

All lab reportsEvery Sermorelin batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Growth speedClinical

8 cm/yr

In a one-year study of 110 children with growth hormone deficiency, sermorelin nearly doubled growth speed, from 4.1 to 8.0 cm a year after 6 months.

vs 4.1 cm/yr at baseline

JCEM 1996 · open-label trial, n=110

Sermorelin

Mean growth speed: 4.1, 8.0 and 7.2 cm a year

Older adultsClinical

+40%

In interim results from placebo-controlled trials of healthy older adults, nightly sermorelin doubled men's 24-hour growth hormone output and raised their IGF-1 about 40%.

vs pre-treatment levels

24-h GH (men)IGF-1 (men)

Interim results in healthy older men

Dialogues Clin Neurosci 2001 · interim RCT data

Immune cellsClinical

+50%

In 19 healthy older adults, 16 weeks of a close analogue of sermorelin raised B-cell numbers by 30% and T-cell responses by 50%.

vs pre-treatment baseline

B cells+30%

T-cell response+50%

Change after 16 weeks, healthy older adults

JCEM 1997 · single-blind trial, n=19