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MOTS-c

A mitochondrial peptide that reshaped metabolism in mice

$69/ 10mg vial

$34.50 per vial with Buy 1, Get 1 Free

1

In stock

  • 99.90% pure on this exact lot, verified by an independent lab, not by us
  • Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
  • Retest it at any lab. If it doesn't match our report, every dollar back
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All products currently listed on this site are for research purposes only.

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

  • Lot-specific HPLC purity + LC-MS identity
  • Raw chromatogram + mass confirmation attached
  • Signed off by the lab's Principal Chemist
  • Permanent archive — searchable by lot ID
MOTS-c · 10mgLot MS10-WM2608-001Live

Purity by HPLC-UV

99.90%

Tested by
Accurate Lab Tests
Tested on
01 Oct 2026
Net content
13.02 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents
See all lab reports
MOTS-c 10mg — molecular specimen
AMPK activationenergy sensor
Insulin signalingglucose handling
Nuclear signalinggene regulation

How MOTS-c works

Researchers study MOTS-c as a signal linking mitochondria to whole-body metabolism through three main routes.

01

AMPK activationenergy sensor

MOTS-c is studied for switching on AMPK, the cell's master fuel gauge that ramps up glucose uptake and fat burning when energy runs low.

02

Insulin signalingglucose handling

In preclinical models it appears to improve how tissues respond to insulin, helping cells clear sugar from the blood more efficiently.

03

Nuclear signalinggene regulation

Under metabolic stress the peptide moves into the cell nucleus, where studies suggest it helps switch on antioxidant and metabolic genes.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of MOTS-c we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

4 batches on record · latest tested 01 Oct 2026

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Running capacityPreclinical
2×

In old mice (22 months), 2 weeks of daily MOTS-c doubled treadmill running time and raised distance 2.16-fold vs untreated old mice.

vs untreated old mice
Nat Commun 2021 · mouse study
UntreatedBaseline
MOTS-c2.16×

Treadmill running distance after 2 weeks

Exercise signalClinical
11.9×

In 10 inactive young men, a session of hard cycling intervals raised the body's own MOTS-c in thigh muscle 11.9-fold over pre-exercise levels.

vs each man's pre-exercise level

Relative MOTS-c level in thigh muscle biopsies

Insulin responsePreclinical
+30%

In mice, 7 days of MOTS-c raised whole-body insulin sensitivity by about 30%, measured as the extra glucose needed to hold blood sugar steady.

vs untreated mice
UntreatedBaseline
MOTS-c+30%

Glucose infusion rate during an insulin clamp test

What buyers say

Common questions

Quick answers about MOTS-c.

99.90% pure, or your money back.

Test any batch at any lab you like. If it doesn't match our report, you get every dollar back. No return shipping, no forms, no arguments.

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