What is L-Glutathione and where does it come from?

L-Glutathione is a tripeptide — a molecule made of three amino acids (cysteine, glutamate, and glycine) — that cells produce naturally as their primary antioxidant. It carries CAS number 70-18-8 and shows up in virtually every tissue. Researchers care about it because it sits at the center of how cells handle oxidative stress and clear toxins.

What has research shown about L-Glutathione?

Preclinical work has explored it as a tissue protector: animal studies have paired antioxidant support with heat stress, liver toxins like carbon tetrachloride, and chemotherapy agents. These models suggest a protective, damage-reducing direction rather than proving any human outcome. All findings are hedged and tied to the specific animal or lab model used.

Is L-Glutathione FDA approved?

L-Glutathione is not approved as a drug for the uses studied here. It appears in some dietary and clinical contexts, but the material sold on this page is research-grade and supplied for in-vitro and laboratory research use only — not for human or veterinary use.

How is L-Glutathione used in research settings?

It's typically used in vitro or in animal models to study oxidative stress, cellular detox pathways, and tissue protection. Researchers often measure the ratio of its reduced to oxidized form as a readout of a cell's redox state. It's supplied here as a lyophilised powder for qualified labs to reconstitute for their own assays.

What is the molecular structure of L-Glutathione?

Its molecular formula is C10H17N3O6S with a molecular weight of 307.32 g/mol. The key structural feature is the free thiol (-SH) group on its cysteine residue — that reactive sulfur is what lets it neutralize reactive compounds and drive its antioxidant activity.

L-Glutathione

The cell's master antioxidant, studied for tissue protection

99.31% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$99/ 1,500mg vial

$49.50 per vial with Buy 1, Get 1 Free

Buy 1, Get 1 Free — add 2 to cart, applied automatically

In stock

99.31% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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All products currently listed on this site are for research purposes only.

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

or browse the lot archive

L-Glutathione · 1,500mgLot GTT1500-WM2607-001Live

Purity by HPLC-UV

99.31%

Tested by: Accurate Lab Tests
Tested on: 20 Aug 2026
Net content: 1506.82 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

Live batch data

Accurate Lab Tests

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot GTT1500-WM2607-001Verified

L-Glutathione 1,500mg

HPLC purity

99.31%

Pass · Meets spec

Tested

20 Aug 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content1506.82 mgPASS

HPLC Chromatogram

Main peak 99.31% · other 0.69%

Alex JohnsonPrincipal Chemist

Authentichain

L-Glutathione 1500mg — molecular specimen

AntioxidantROS scavenging

Detoxconjugation

Redox balanceGSH/GSSG cycle

How L-Glutathione works

Researchers study L-Glutathione as acting through three distinct routes inside the cell.

AntioxidantROS scavenging

It's studied for directly neutralizing reactive oxygen species — the unstable molecules that damage cell components under stress.

Detoxconjugation

It's investigated for binding to toxins and chemical byproducts so cells can package and clear them, a route explored in liver-injury models.

Redox balanceGSH/GSSG cycle

It cycles between reduced and oxidized forms, and researchers track that ratio as a marker of a cell's overall oxidative state.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of L-Glutathione we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

3 batches on record · latest tested 20 Aug 2026

All lab reportsEvery L-Glutathione batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Walking distanceClinical

196 m

In a placebo-controlled trial of 40 people with leg artery disease, 5 days of glutathione infusions raised pain-free walking distance from 143 to 196 m, while saline did not.

vs 143 m before; saline unchanged

Mayo Clin Proc 2002 · RCT, n=40

Pain-free walking distance on a treadmill

Body storesClinical

+30–35%

In a 6-month placebo-controlled trial of 54 adults, oral glutathione at the higher dose raised glutathione 30% to 35% in blood cells and plasma, and 260% in cheek cells.

vs starting levels, higher dose

Red cells, plasma, lymphocytes+30–35%

Cheek cells+260%

Rise in glutathione levels at 6 months, higher dose

Eur J Nutr 2015 · RCT, n=54

Immune cellsClinical

>2×

In the same 54-adult trial, the killing activity of natural killer immune cells more than doubled by 3 months on high-dose oral glutathione vs placebo.

vs placebo at 3 months

Placebo1×

Glutathione, high dose>2×

Natural killer cell killing activity at 3 months, vs placebo

Eur J Nutr 2015 · RCT, n=54