What exactly is ipamorelin and where did it come from?

Ipamorelin is a synthetic pentapeptide — a chain of five amino acids — developed in the 1990s as a selective growth-hormone secretagogue. It was designed to copy ghrelin's action at the pituitary while avoiding the hormone side effects seen with earlier peptides. Its molecular formula is C38H49N9O5 with a molecular weight of 711.86 g/mol.

What has research actually shown about it?

In animal and cell studies, ipamorelin prompted release of growth hormone from the pituitary by activating the GHS-R1a receptor. What set it apart in that early work was selectivity — it did this without the notable cortisol or prolactin spikes that other secretagogues caused. All of this is preclinical; effects in humans are not established here.

Is ipamorelin FDA approved?

No. Ipamorelin is not approved by the FDA for any use and there is no marketed drug product based on it. The material sold here is a research chemical supplied strictly for in-vitro and laboratory research use only — not for human or veterinary use.

How does ipamorelin differ from other growth-hormone peptides like GHRP-6?

Both act on the ghrelin/GHS receptor, but ipamorelin is studied as more selective — GHRP-6 tends to also drive appetite and can nudge cortisol and prolactin. Researchers often reach for ipamorelin when they want a cleaner growth-hormone signal to study without those extra effects clouding the readout.

What is the molecular structure of ipamorelin?

Ipamorelin has the molecular formula C38H49N9O5 and a molecular weight of 711.86 g/mol (CAS 170851-70-4). It's a short pentapeptide, and its key feature is a design that keeps it selective for the growth-hormone secretagogue receptor. Identity is confirmed by LC-MS on every lot.

Ipamorelin

A clean growth-hormone trigger with almost no side spillover

99.51% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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99.51% pure on this exact lot, verified by an independent lab, not by us
Tested in America. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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Certificate of analysis

Every vial ships with its own report

We don't publish a brand-wide spec sheet and call it a “COA.” The certificate you receive references the actual lot number stamped on your vial — with the raw chromatograms attached.

Lot-specific HPLC purity + LC-MS identity
Raw chromatogram + mass confirmation attached
Signed off by the lab's Principal Chemist
Permanent archive — searchable by lot ID

or browse the lot archive

Ipamorelin · 10mgLot 4T7FHJLive

Purity by HPLC-UV

99.51%

Tested by: Freedom Diagnostics
Tested on: 17 Aug 2026
Net content: 12.26 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

Live batch data

Freedom Diagnostics

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot 4T7FHJVerified

Ipamorelin 10mg

HPLC purity

99.51%

Pass · Meets spec

Tested

17 Aug 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content12.26 mgPASS

HPLC Chromatogram

Main peak 99.51% · other 0.49%

Alex JohnsonPrincipal Chemist

Authentichain · Verified 15×

GHS-R1areceptor agonist

GH pulsepituitary release

Selectivitylow off-target

How Ipamorelin works

Researchers study ipamorelin through three connected routes tied to how it engages the ghrelin system.

GHS-R1areceptor agonist

It binds the growth-hormone secretagogue receptor on pituitary cells, the same docking site the natural hormone ghrelin uses.

GH pulsepituitary release

Activating that receptor is studied to trigger a burst of growth hormone from the pituitary rather than a flat continuous rise.

Selectivitylow off-target

Unlike broader secretagogues, it's studied for leaving cortisol and prolactin signalling largely alone, keeping the effect narrow.

For research use only. Mechanisms described reflect published preclinical and clinical literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of Ipamorelin we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

4 batches on record · latest tested 17 Aug 2026

All lab reportsEvery Ipamorelin batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Selective GH releasePreclinical

>200×

In pigs, ipamorelin released about as much growth hormone as GHRP-6 without raising stress hormones ACTH or cortisol, even at over 200 times its half-strength dose.

times its half-strength dose

Eur J Endocrinol 1998 · pig and rat study

GHRP-256 ng/mL

Ipamorelin65 ng/mL

GHRP-674 ng/mL

Peak GH in pigs; GHRP-2 and GHRP-6 also raised cortisol

GH pulseClinical

2 h

In healthy men given ipamorelin, growth hormone rose in a single pulse that peaked within the first hour and faded to near zero, and ipamorelin's half-life was 2 hours.

ipamorelin plasma half-life

Infusion

over 15 minutes

GH peaks

at 0.67 h

Peptide clears

half-life 2 h

GH back near zero

one pulse, every dose

Response to one infusion in healthy men

Pharm Res 1999 · human trial, n=8 per dose

Steroid modelPreclinical

4×

In adult rats given steroids for 3 months, adding ipamorelin raised calf muscle strength and made the outer bone surface build new bone four times faster than steroids alone.

vs glucocorticoid alone

Steroid alone1×

Steroid + ipamorelin4×

Bone formation rate at the outer bone surface, 3 months

Growth Horm IGF Res 2001 · rat study